Investigating how environmental factors affect obesity through genetic changes
Novel imprint control regions (ICRs) responsive to environmental exposures
This study is looking at how things in our environment might affect obesity in kids aged 0-11 by checking certain genes and how they change over time, hoping to find new ways to understand and tackle obesity.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-10880569 on NIH RePORTER |
What this research studies
This research explores the relationship between environmental exposures and obesity by examining specific genetic regions that may influence obesity risk. It aims to identify epigenetic mechanisms that mediate these associations, particularly in children aged 0-11 years. The study will utilize advanced techniques to measure DNA methylation changes over time and across different cell types, which could provide insights into how these changes relate to obesity outcomes. By developing a comprehensive screening tool, the research seeks to enhance our understanding of obesity and its underlying genetic factors.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who may be at risk for obesity due to environmental influences.
Not a fit: Patients outside the age range of 0-11 years or those not affected by obesity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for obesity in children by identifying genetic markers influenced by environmental factors.
How similar studies have performed: Previous research has shown promising results in understanding the role of epigenetics in obesity, suggesting that this approach could yield valuable insights.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Hoyo, Cathrine — North Carolina State University Raleigh
- Study coordinator: Hoyo, Cathrine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.