Investigating how environmental factors affect liver disease severity in adults
Exposome and Precision Medicine in NAFLD
This study is looking at how things in our environment might affect the severity of nonalcoholic fatty liver disease (NAFLD) in adults, especially those dealing with obesity and metabolic issues, to help improve care for people with this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Louisville NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project ID | NIH-10472017 on NIH RePORTER |
What this research studies
This research focuses on nonalcoholic fatty liver disease (NAFLD), the most common liver disease linked to obesity and metabolic issues. It aims to understand how environmental exposures influence the severity and progression of NAFLD in adults. By forming a virtual consortium of experts, the project will analyze data from various centers to identify key environmental factors and their impact on liver health. This approach combines advanced methodologies to bridge existing knowledge gaps and improve patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with nonalcoholic fatty liver disease (NAFLD).
Not a fit: Patients with liver diseases unrelated to nonalcoholic fatty liver disease or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatment strategies for patients with NAFLD based on their environmental exposures.
How similar studies have performed: Previous studies have shown promising results in understanding the environmental contributions to liver diseases, making this approach both relevant and potentially impactful.
Where this research is happening
Louisville, United States
- University of Louisville — Louisville, United States (Active)
Researchers
- Principal investigator: Cave, Matthew C — University of Louisville
- Study coordinator: Cave, Matthew C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.