Investigating how environmental factors affect Alzheimer's disease and related dementias

The Study of the Environment and Alzheimer's disease and related Dementias (SEAD)

['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11039973

This study is looking at how things in our environment, like lead and cadmium, might affect the chances of developing Alzheimer's disease and other types of dementia, using a big set of health data collected over 25 years to help find ways to prevent these conditions.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-11039973 on ClinicalTrials.gov

What this research studies

This research explores the connection between environmental exposures, such as lead and cadmium, and the risk of developing Alzheimer's disease and related dementias (ADRD). By utilizing a large dataset from the National Health and Nutrition Examination Survey, the study aims to systematically evaluate various environmental factors and their impact on ADRD incidence. The approach includes analyzing long-term exposure data and linking it to health outcomes over a span of 25 years. This could provide valuable insights into prevention strategies and public health policies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have been exposed to environmental toxins and are at risk for Alzheimer's disease or related dementias.

Not a fit: Patients who do not have any risk factors for Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for Alzheimer's disease and related dementias.

How similar studies have performed: Previous research has indicated that environmental factors can influence the risk of Alzheimer's disease, suggesting that this approach may yield significant findings.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: advanced disease, Alzheimer disease dementia, Alzheimer syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.