Investigating how environmental exposures affect lung health in people at risk for pulmonary fibrosis
Official title: Project 2: Environmental exposures in pre-clinical FPF
Funded at University of Michigan at Ann Arbor · NIH-10846189 · Data updated 2026-11-12
This study is looking at how things in our environment, like air pollution and chemicals, might affect the development of pulmonary fibrosis, a serious lung disease, and it's for people who have a family history of this condition; participants will have tests like CT scans and blood tests to help us learn more about the disease and how to catch it early.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 17, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $399,950 |
| NIH project number | 1P01HL172729-01 |
| Project ID | NIH-10846189 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include middle-aged adults with a family history of pulmonary fibrosis or those showing early signs of lung abnormalities.
✕Less likely to help
Patients without a family history of pulmonary fibrosis or those who do not exhibit any lung abnormalities may not benefit from this research.
What this research studies
This research focuses on understanding the role of environmental exposures, such as air pollutants and chemicals, in the development of pulmonary fibrosis (PF), a serious lung disease. By studying a cohort of individuals who are at risk for familial PF, the research aims to identify how these exposures contribute to disease progression and pathology. Participants will undergo assessments including CT scans and blood tests to evaluate lung health and biological markers. The goal is to integrate findings from various scientific disciplines to better understand the disease and improve early diagnosis.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for early detection and prevention of pulmonary fibrosis, ultimately enhancing patient outcomes.
How similar studies have gone: Previous research has shown promising results in understanding the impact of environmental factors on lung diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Salisbury, Margaret Louise — University of Michigan at Ann Arbor
- Study coordinator: Salisbury, Margaret Louise
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.