Investigating how environmental chemicals affect mood and cognition in postmenopausal women.
Understanding the Relationship Between Environmental Endocrine Disrupting Chemicals, Neuropsychiatric Outcomes, and Related Biological Processes in Depression
['FUNDING_OTHER'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10913574
This study is looking at how certain chemicals in the environment might affect mood and thinking skills in postmenopausal women, especially those who have experienced depression, to better understand how these chemicals could impact mental health as we age.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10913574 on ClinicalTrials.gov |
What this research studies
This research explores the impact of environmental endocrine disrupting chemicals (EDCs) on mood and cognitive function, particularly in postmenopausal women. It aims to understand the relationship between EDC exposure and neuropsychiatric symptoms, such as depression and cognitive decline. The study will evaluate both women with a history of major depression and healthy controls, assessing various biological markers that may mediate these effects. By examining these associations, the research seeks to shed light on how ongoing exposure to EDCs may influence mental health outcomes in later life.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women, particularly those with a history of major depression or those experiencing neuropsychiatric symptoms.
Not a fit: Patients who are not postmenopausal or do not have a history of mood disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of depression and cognitive dysfunction in postmenopausal women.
How similar studies have performed: While there is emerging evidence linking EDCs to neuropsychiatric outcomes, this specific focus on postmenopausal women is relatively novel and underexplored.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HARDER, JESSICA ANN — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: HARDER, JESSICA ANN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Affective Disorders