Investigating how environmental chemicals affect male fertility and reproductive health.
Seminal plasma metabolomic signatures, preconception phthalates and reproductive outcomes.
['FUNDING_R01'] · WAYNE STATE UNIVERSITY · NIH-10939815
This study is looking at how certain chemicals found in plastics and personal care products might affect men's fertility, and it aims to find new ways to measure male reproductive health to help couples who are having trouble getting pregnant.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAYNE STATE UNIVERSITY (nih funded) |
| Locations | 1 site (DETROIT, UNITED STATES) |
| Trial ID | NIH-10939815 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the impact of phthalates, common environmental chemicals found in plastics and personal care products, on male fertility. It aims to identify novel biomarkers in seminal plasma that can provide insights into male reproductive health and how these biomarkers are influenced by exposure to these chemicals. By analyzing the composition of seminal plasma, the research seeks to improve diagnostic tools for assessing male fertility and ultimately enhance reproductive outcomes for couples facing infertility.
Who could benefit from this research
Good fit: Ideal candidates for this research include couples experiencing difficulty conceiving, particularly those where male factors may contribute to infertility.
Not a fit: Patients who are not experiencing infertility or those whose infertility is solely attributed to female factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic methods and treatments for male infertility, improving the chances of conception for couples.
How similar studies have performed: Previous research has shown promising results in identifying biomarkers related to male fertility, suggesting that this approach could yield valuable insights.
Where this research is happening
DETROIT, UNITED STATES
- WAYNE STATE UNIVERSITY — DETROIT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PILSNER, J. RICHARD — WAYNE STATE UNIVERSITY
- Study coordinator: PILSNER, J. RICHARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.