Investigating how energy use can indicate aging through thermal imaging

Testing energy expenditures as biomarkers of aging using thermal imaging in a controlled environment

NIH-funded research Scintillon Institute for Photobiology · NIH-10952949

This study is looking at how our bodies use energy as we get older by watching how active rodents are in a special setup that uses thermal imaging, which could help us learn more about aging and metabolism.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionScintillon Institute for Photobiology NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-10952949 on NIH RePORTER

What this research studies

This research focuses on understanding how energy expenditure changes with age by using thermal imaging technology in a controlled environment. By studying rodent models, the researchers aim to identify age-related changes in physical activity energy expenditure (PAEE) and total energy expenditure (TEE) as potential biomarkers of aging. The study utilizes a novel platform called ENTICE, which allows for continuous thermal imaging and monitoring of animal behaviors, providing real-time data on energy use. This approach seeks to improve our understanding of aging and its effects on metabolism and physical activity.

Who could benefit from this research

Good fit: Ideal candidates for this research would be individuals interested in the biological mechanisms of aging and those with age-related conditions, particularly Alzheimer's disease.

Not a fit: Patients who are not affected by aging or do not have age-related diseases may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to new methods for assessing aging and related diseases, potentially improving early detection and treatment strategies.

How similar studies have performed: While the use of energy expenditure as a biomarker is established, the specific application of thermal imaging in this context is relatively novel and has not been extensively tested.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.