Investigating how endosomes and mitochondria interact in breast cancer cells
Endosome-mitochondria interactions in breast cancer cells
This study is looking at how tiny parts of breast cancer cells work together to affect how the cancer grows and spreads, with the hope of finding new ways to treat and diagnose breast cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albany Medical College NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project ID | NIH-10771998 on NIH RePORTER |
What this research studies
This research explores the interactions between early endosomes and mitochondria in breast cancer cells to understand how these interactions influence cancer-related processes such as cell growth, movement, and invasiveness. By examining these cellular components in a three-dimensional culture environment, the study aims to uncover how changes in endosomal function can affect signaling pathways and iron balance within cancer cells. The goal is to identify new therapeutic targets and diagnostic tools that could improve treatment outcomes for breast cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with breast cancer who are interested in innovative treatment approaches.
Not a fit: Patients with non-cancerous conditions or those who do not have breast cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating breast cancer by targeting the cellular mechanisms that promote tumor growth and spread.
How similar studies have performed: While the specific approach of studying endosome-mitochondria interactions in breast cancer is novel, similar research has shown promise in understanding cellular processes in other cancer types.
Where this research is happening
Albany, United States
- Albany Medical College — Albany, United States (Active)
Researchers
- Principal investigator: Barroso, Margarida — Albany Medical College
- Study coordinator: Barroso, Margarida
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.