Investigating how endocrine disrupting chemicals affect male neurobehavioral disorders.
Official title: Endocrine Disrupting Chemicals and Male-biased Neurobehavioral Disorders
Funded at University of Rochester · NIH-10992140 · Data updated 2026-11-12
This study is looking at how everyday chemicals that can disrupt hormones might affect brain development in boys with ADHD and Autism, hoping to find ways to help prevent and treat these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | February 3, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $336,242 |
| NIH project number | 5R01ES034829-03 |
| Project ID | NIH-10992140 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children, particularly males, who are at risk for or diagnosed with neurodevelopmental disorders such as ADHD or Autism Spectrum Disorders.
✕Less likely to help
Patients who are not male or do not have neurodevelopmental disorders may not receive direct benefits from this research.
What this research studies
This research focuses on understanding the impact of endocrine disrupting chemicals (EDCs) on neurodevelopmental disorders like ADHD and Autism Spectrum Disorders in children. It examines how these chemicals, which are often found in everyday products, may contribute to the male bias observed in these disorders. The study utilizes a curated mixture of EDCs to analyze their effects on testosterone levels and subsequent behavioral changes in male mice, which may mirror similar effects in humans. By identifying the mechanisms behind these disorders, the research aims to provide insights into prevention and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for neurodevelopmental disorders in children.
How similar studies have gone: Previous studies have indicated a link between EDC exposure and neurodevelopmental disorders, suggesting that this research builds on established findings rather than exploring an entirely novel approach.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Terry, Marissa Sobolewski — University of Rochester
- Study coordinator: Terry, Marissa Sobolewski
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.