Investigating how eating mushrooms affects brain health in older adults

Longitudinal cohort of mushroom intake and cognitive function in the elderly

NIH-funded research Pennsylvania State Univ Hershey Med Ctr · NIH-10987524

This study is looking at how eating mushrooms might help improve thinking and memory in middle-aged and older people in Aichi Prefecture, Japan, to see if they can help keep our minds sharp as we age.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionPennsylvania State Univ Hershey Med Ctr NIH-funded
Lab location1 site (Hershey, United States)
Project IDNIH-10987524 on NIH RePORTER

What this research studies

This research aims to explore the relationship between mushroom consumption and cognitive function in middle-aged and elderly individuals in Aichi Prefecture, Japan. The study will assess dietary habits and cognitive performance, focusing on the potential benefits of mushrooms, which are rich in antioxidants and anti-inflammatory compounds. By analyzing data from cognitive tests and dietary surveys, the research seeks to identify specific foods that may help delay cognitive decline in older adults. Participants will be monitored over time to evaluate changes in cognitive abilities related to their mushroom intake.

Who could benefit from this research

Good fit: Ideal candidates for this research are healthy adults aged 21 and older, particularly those who are middle-aged or elderly and interested in dietary impacts on cognitive health.

Not a fit: Patients who do not consume mushrooms or have dietary restrictions that prevent them from including mushrooms in their diet may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to dietary recommendations that help improve cognitive health and reduce the risk of dementia in older adults.

How similar studies have performed: Previous studies have shown positive associations between mushroom consumption and cognitive function, suggesting that this research builds on existing knowledge rather than exploring an entirely novel concept.

Where this research is happening

Hershey, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.