Investigating how early life immune responses and environmental exposures affect allergic diseases in children.
Immune Development Across the Life Course: Integrating Exposures and Multi-Omics in the Boston Birth Cohort
['FUNDING_U01'] · JOHNS HOPKINS UNIVERSITY · NIH-10871861
This study is looking at how kids' immune systems grow from birth to 18 years old and how things like germs and pollution might affect their chances of developing allergies, so if you're a parent in the Boston area, your family's participation could help us learn more about keeping children healthy!
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10871861 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how the immune system develops in children from birth to age 18, particularly in relation to exposure to various microbes and environmental pollutants. By studying a large group of mother-child pairs from the Boston Birth Cohort, the researchers aim to uncover the connections between early life exposures and the risk of developing allergic diseases. The study utilizes advanced techniques, including multi-omics analysis, to explore the molecular pathways involved in these immune responses. Participants will contribute to a better understanding of how early life factors influence long-term health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include children from birth to 18 years old, particularly those with a family history of allergies or asthma.
Not a fit: Patients who are adults or do not have any history of allergic diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for allergic diseases in children.
How similar studies have performed: Previous research has shown success in understanding immune responses and environmental impacts on health, making this approach promising.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, XIAOBIN — JOHNS HOPKINS UNIVERSITY
- Study coordinator: WANG, XIAOBIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Allergic Disease