Investigating how early hearing loss may relate to Alzheimer's disease
Early Age-Related Hearing Loss Investigation (EARHLI): A Randomized Controlled Trial to Assess Mechanisms Linking Early Age-Related Hearing Loss and Alzheimer's Disease and Related Dementias
['FUNDING_R01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10911957
This study is looking at how using hearing aids might help people aged 55 to 75 with early hearing loss and mild memory issues, by seeing if better hearing can improve their thinking skills and social connections, possibly helping to prevent further memory decline.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10911957 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the connection between early age-related hearing loss and the risk of developing Alzheimer's disease and related dementias. It involves a randomized controlled trial where participants aged 55 to 75 with early-stage hearing loss and mild cognitive impairment will receive hearing aids to assess their impact on cognitive decline. The study aims to explore how improving hearing may enhance social engagement and brain connectivity, potentially preventing further cognitive deterioration. Participants will be monitored to gather data on the effectiveness of this intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 55 to 75 who have early-stage age-related hearing loss and mild cognitive impairment.
Not a fit: Patients who do not have hearing loss or those with advanced Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing cognitive decline in individuals at risk for Alzheimer's disease.
How similar studies have performed: Previous studies have suggested that hearing aids can improve social engagement and cognitive function, indicating potential success for this approach.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOLUB, JUSTIN SCOTT — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: GOLUB, JUSTIN SCOTT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.