NIH-funded research Career grant

Investigating how e-cigarette use affects smoking behavior

Official title: Using Causal Machine Learning Methods to Inform Tobacco Regulatory Science

Funded at New York University · NIH-11082227 · Data updated 2026-11-12

This study is looking at how using e-cigarettes might affect whether people start smoking regular cigarettes, and it’s for anyone interested in understanding how different factors like age and gender play a role in this relationship.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionNew York University
NIH-funded
Lab location1 site (New York, United States)
Project startMay 1, 2023
Project endApril 30, 2028
Funding year2025
Award (this year)$187,877
NIH project number5K01DA058408-03
Project IDNIH-11082227 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals aged 21 and older who use e-cigarettes or combustible cigarettes.

Less likely to help

Patients who do not use tobacco products or e-cigarettes may not benefit from this research.

What this research studies

This research aims to clarify the relationship between e-cigarette (EC) use and subsequent combustible cigarette (CC) smoking behaviors. By employing causal machine learning methods, the study will analyze complex data to understand how various factors, such as age and gender, influence the effects of EC use on smoking habits. The goal is to identify specific characteristics that may modify these effects, which could help inform tobacco regulation and address health disparities. The findings could provide critical insights for policymakers regarding the impact of e-cigarettes on smoking behaviors across different populations.

Why it matters

Potential benefit: If successful, this research could lead to more effective tobacco regulations that reduce smoking rates and improve public health.

How similar studies have gone: Previous research has shown mixed results regarding the impact of e-cigarettes on smoking behaviors, indicating that this area is still being explored and holds potential for new insights.

Where this research is happening

  • New York University
    New York, United States
    Active

Researchers

  • Principal investigator: Xu, Shu — New York University
  • Study coordinator: Xu, Shu

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.