Investigating how drugs are metabolized and absorbed in the body
IN VITRO METABOLISM AND NON-CLINICAL ADME STUDIES IDIQ CONTRACT. POP 9/27/21-9/26/26. NTE $3.5 MILLION. FIRST TASK ORDER 01 OBLIGATED IN THE AMOUNT O
This study is looking at how the body handles medications to help create new and safer treatments for people dealing with substance use disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sri International NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project ID | NIH-10505766 on NIH RePORTER |
What this research studies
This research focuses on understanding how medications are processed in the body through in vitro and in vivo studies. It aims to analyze the metabolism and permeability of drugs to support the development of new medications, particularly for substance use disorders. The data collected will be used to assist in the submission of new drug applications to the FDA, ensuring that new treatments are safe and effective for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are seeking new treatment options for substance use disorders.
Not a fit: Patients who are not affected by substance use disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of safer and more effective medications for patients with substance use disorders.
How similar studies have performed: Previous research in drug metabolism and ADME studies has shown success in developing new medications, indicating that this approach is well-established.
Where this research is happening
Menlo Park, United States
- Sri International — Menlo Park, United States (Active)
Researchers
- Principal investigator: Bastida, Mary — Sri International
- Study coordinator: Bastida, Mary
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.