Investigating how DNA interacts with a special material to improve genetic testing
Charge Transfer Study of DNA/MoS2 interface
['FUNDING_R15'] · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · NIH-10798439
This study is exploring how DNA interacts with a special material called molybdenum disulfide to create a new, easier way to test for genetic disorders that could give more accurate results without complicated steps.
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (nih funded) |
| Locations | 1 site (CARBONDALE, UNITED STATES) |
| Trial ID | NIH-10798439 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the electrical properties of DNA when it is in contact with molybdenum disulfide (MoS2), a material that could enhance genetic testing methods. By studying how DNA repeats transfer electrical charges, the researchers aim to develop a new, label-free sensing platform that could provide more accurate genetic testing for various disorders. The project involves both theoretical and experimental approaches, including advanced microscopy techniques to validate findings. This innovative method seeks to overcome the limitations of current genetic testing technologies, which often yield false results or require complex procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by genetically transferrable disorders linked to tandem DNA repeats.
Not a fit: Patients with disorders not related to DNA mutations or those not affected by tandem DNA repeats may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and efficient genetic testing for disorders caused by DNA mutations.
How similar studies have performed: While the approach of using MoS2 for DNA sensing is innovative, similar research has shown promise in enhancing genetic testing accuracy.
Where this research is happening
CARBONDALE, UNITED STATES
- SOUTHERN ILLINOIS UNIVERSITY CARBONDALE — CARBONDALE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHAMSI, MOHTASHIM H — SOUTHERN ILLINOIS UNIVERSITY CARBONDALE
- Study coordinator: SHAMSI, MOHTASHIM H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.