Investigating how different types of brain cells affect memory and aging in Alzheimer's disease

Who could benefit from this research

What this research studies

This research focuses on understanding the role of microglia, a type of brain cell, in maintaining cognitive function as people age and in the context of Alzheimer's disease. The project aims to integrate various data sources, including brain imaging and postmortem analysis, to explore how these cells contribute to cognitive resilience. By using advanced imaging techniques, researchers will study microglial behavior in mouse models of Alzheimer's, which may provide insights into how to protect memory and cognitive abilities in aging individuals. The findings could lead to new strategies for enhancing brain health in older adults.

Why it matters

Where this research is happening

• Mayo Clinic Rochester
  Rochester, United States Active

Researchers

• Principal investigator: Nguyen, Aivi Thanh — Mayo Clinic Rochester
• Study coordinator: Nguyen, Aivi Thanh

Related research

Other NIH-funded projects on the same topics.

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• Cognitive SuperAging: Exploring why some octogenarians stay sharp in memory

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.