Investigating how different tobacco products affect toxicity and addiction

Penn State TCORS: Tobacco Product Composition Effects on Toxicity and Addiction

['FUNDING_OTHER'] · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · NIH-11087192

This study is looking at how different tobacco products, like e-cigarettes and nicotine pouches, affect our health and addiction, so that the FDA can create better rules to help reduce the harm they cause.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorPENNSYLVANIA STATE UNIV HERSHEY MED CTR (nih funded)
Locations1 site (HERSHEY, UNITED STATES)
Trial IDNIH-11087192 on ClinicalTrials.gov

What this research studies

This research aims to provide a scientific foundation for the FDA to implement regulations that reduce the harm caused by tobacco products. It involves a collaboration of experienced scientists who will conduct basic and translational research on the toxicity and addiction potential of various tobacco products, including e-cigarettes and nicotine pouches. The study will focus on understanding the biological effects of oxidants found in tobacco smoke and aerosols, and how product design influences these effects. By developing new research methods, the findings could inform future tobacco regulations and harm reduction strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who currently use tobacco products, such as e-cigarettes or cigars.

Not a fit: Patients who do not use tobacco products or have never been exposed to tobacco may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer tobacco products and reduced health risks for users.

How similar studies have performed: Previous research has shown promising results in understanding the effects of tobacco product design on addiction and toxicity, indicating that this approach has potential for success.

Where this research is happening

HERSHEY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.