Investigating how different nicotine levels in e-cigarettes affect health and smoking behaviors
Official title: Effects of Nicotine Concentration Levels in E-cigarettes on Biomarkers of Exposure to Toxicants and Tobacco Use Behaviors
Funded at University of Nebraska Medical Center · NIH-10917171 · Data updated 2026-11-12
This study is looking at how different amounts of nicotine in e-cigarettes affect your health and smoking habits, especially for people who currently smoke or have quit, to help improve public health guidelines.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $233,396 |
| NIH project number | 5R21DA058328-02 |
| Project ID | NIH-10917171 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include current and former smokers aged 18 years and older who use e-cigarettes.
✕Less likely to help
Patients who do not use e-cigarettes or are never smokers may not benefit from this research.
What this research studies
This research examines the impact of varying nicotine concentrations in e-cigarettes on health markers and smoking behaviors. By analyzing biological samples and behavioral data, the study aims to understand how different levels of nicotine affect users, particularly focusing on both current and former smokers. The research will involve participants using e-cigarettes with different nicotine levels to assess their exposure to harmful substances and changes in smoking habits. This information could help inform public health policies and product regulations.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and regulation of e-cigarette products, potentially reducing health risks for users.
How similar studies have gone: Previous research has shown that nicotine levels in tobacco products can significantly influence health outcomes and smoking behaviors, indicating that this approach has merit.
Where this research is happening
-
University of Nebraska Medical Center
Omaha, United States Active
Researchers
- Principal investigator: Dai, Hongying Daisy — University of Nebraska Medical Center
- Study coordinator: Dai, Hongying Daisy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.