Investigating how different nicotine levels in e-cigarettes affect health and smoking behaviors

Effects of Nicotine Concentration Levels in E-cigarettes on Biomarkers of Exposure to Toxicants and Tobacco Use Behaviors

NIH-funded research University of Nebraska Medical Center · NIH-10917171

This study is looking at how different amounts of nicotine in e-cigarettes affect your health and smoking habits, especially for people who currently smoke or have quit, to help improve public health guidelines.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Nebraska Medical Center NIH-funded
Lab location1 site (Omaha, United States)
Project IDNIH-10917171 on NIH RePORTER

What this research studies

This research examines the impact of varying nicotine concentrations in e-cigarettes on health markers and smoking behaviors. By analyzing biological samples and behavioral data, the study aims to understand how different levels of nicotine affect users, particularly focusing on both current and former smokers. The research will involve participants using e-cigarettes with different nicotine levels to assess their exposure to harmful substances and changes in smoking habits. This information could help inform public health policies and product regulations.

Who could benefit from this research

Good fit: Ideal candidates for this research include current and former smokers aged 18 years and older who use e-cigarettes.

Not a fit: Patients who do not use e-cigarettes or are never smokers may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and regulation of e-cigarette products, potentially reducing health risks for users.

How similar studies have performed: Previous research has shown that nicotine levels in tobacco products can significantly influence health outcomes and smoking behaviors, indicating that this approach has merit.

Where this research is happening

Omaha, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer Causing Agents
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.