Investigating how diet affects heart health during calorie restriction
Official title: Examining dietary and metabolomics patterns on cardiometabolic outcome variability in response to calorie restriction
Funded at Lsu Pennington Biomedical Research Ctr · NIH-10999079 · Data updated 2026-11-12
This study is looking at how different eating habits and body chemistry affect health changes in people who are cutting calories, and it’s designed for anyone wanting to improve their blood pressure, cholesterol, and blood sugar while learning to make healthier food choices.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Pennington Biomedical Research Ctr NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project start | August 12, 2024 |
| Project end | August 11, 2026 |
| Funding year | 2024 |
| Award (this year) | $78,328 |
| NIH project number | 1F32HL176217-01 |
| Project ID | NIH-10999079 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are healthy adults who are interested in calorie restriction and improving their cardiometabolic health.
✕Less likely to help
Patients with existing cardiovascular diseases or those who are not able to adhere to dietary changes may not benefit from this research.
What this research studies
This research examines how different dietary patterns and metabolomic profiles influence the variability of cardiometabolic outcomes in individuals undergoing calorie restriction. Participants will be educated on making healthy food choices while reducing their overall calorie intake. The study aims to identify factors that contribute to differences in health outcomes among individuals on calorie restriction, focusing on improvements in blood pressure, blood lipids, and glucose levels. By analyzing data from a large clinical trial, the research seeks to understand how personalized dietary approaches can enhance the effectiveness of calorie restriction.
Why it matters
Potential benefit: If successful, this research could lead to personalized dietary recommendations that improve heart health and reduce the risk of cardiovascular disease.
How similar studies have gone: Previous research has shown that calorie restriction can improve health outcomes, but this study aims to explore new insights into individual dietary responses, making it a novel approach.
Where this research is happening
-
Lsu Pennington Biomedical Research Ctr
Baton Rouge, United States Active
Researchers
- Principal investigator: Woolf, Emily Katlyn — Lsu Pennington Biomedical Research Ctr
- Study coordinator: Woolf, Emily Katlyn
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.