Investigating how diet affects gut bacteria and their interactions with the host

Metaproteomics to investigate intestinal microbiota-host and -diet interactions

NIH-funded research North Carolina State University Raleigh · NIH-11037149

This study is looking at how what you eat affects the bacteria in your gut and your overall health, so you can learn how to improve your gut health through your diet.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorth Carolina State University Raleigh NIH-funded
Lab location1 site (Raleigh, United States)
Project IDNIH-11037149 on NIH RePORTER

What this research studies

This research explores the complex relationships between diet, gut bacteria, and host health. By using advanced techniques like metaproteomics, metagenomics, and metabolomics, the team aims to identify how different dietary proteins and host compounds influence the composition and function of gut microbiota. Patients may benefit from insights into how their diet can affect their gut health and overall well-being. The research combines both laboratory-based and cultivation-independent methods to provide a comprehensive understanding of these interactions.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals interested in understanding how their diet impacts their gut microbiota and those with gastrointestinal disorders.

Not a fit: Patients who do not have gastrointestinal issues or are not interested in dietary impacts on health may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to personalized dietary recommendations that improve gut health and overall patient outcomes.

How similar studies have performed: Previous research has shown promising results in understanding the role of diet on gut microbiota, indicating that this approach could yield valuable insights.

Where this research is happening

Raleigh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.