Investigating how diabetes affects cognitive decline and related brain changes
Association of glycemia and related factors and complications with cognitive impairment and AD/ADRD biomarkers
This study is looking at how type 2 diabetes and pre-diabetes might affect thinking and memory over time, and it's for people with these conditions who want to understand more about their brain health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10924056 on NIH RePORTER |
What this research studies
This research examines the links between type 2 diabetes and cognitive decline, including mild cognitive impairment and dementia, by studying individuals with pre-diabetes and type 2 diabetes. It focuses on various diabetes-related factors such as insulin resistance and advanced glycation end products, and how these may contribute to cognitive issues over time. Participants will be monitored for changes in cognitive function and biomarkers associated with brain health, providing insights into the relationship between diabetes and cognitive impairment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pre-diabetes or type 2 diabetes who are concerned about cognitive health.
Not a fit: Patients without diabetes or those with other unrelated cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cognitive decline in patients with diabetes, potentially improving their quality of life.
How similar studies have performed: Previous research has indicated that diabetes is a significant risk factor for cognitive decline, suggesting that this study's approach is built on established findings.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Dabelea, Dana — Columbia University Health Sciences
- Study coordinator: Dabelea, Dana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.