Investigating how diabetes affects brain function and glucose control
Diabetes, glucose metabolism, and neuroplasticity in the vagal complex
This study is looking at how diabetes affects the brain's ability to control sugar levels in the body, using animal models to see how certain brain cells react to changes in sugar and how this changes in diabetes, with the hope of finding new ways to help treat diabetes and its complications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project ID | NIH-10685540 on NIH RePORTER |
What this research studies
This research explores the relationship between diabetes and the brain's ability to regulate glucose levels. Using animal models, it examines how specific neurons in the brain respond to changes in glucose and how these responses are altered in diabetes. The study aims to uncover the mechanisms behind autonomic dysfunction in diabetes, which can lead to serious health complications. By understanding these processes, the research seeks to identify new targets for diabetes treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with type 1 or type 2 diabetes who are experiencing complications related to glucose regulation.
Not a fit: Patients without diabetes or those with other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for diabetes that address the underlying causes rather than just the symptoms.
How similar studies have performed: Previous research has shown promising results in understanding the brain's role in glucose regulation, suggesting that this approach could yield valuable insights.
Where this research is happening
Fort Collins, United States
- Colorado State University — Fort Collins, United States (Active)
Researchers
- Principal investigator: Smith, Bret N — Colorado State University
- Study coordinator: Smith, Bret N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.