Investigating how deep brain stimulation affects voice and swallowing in Parkinson's disease
Effects of deep brain stimulation (DBS) on laryngeal function and associated behaviors in Parkinson Disease
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10904836
This study is looking at how deep brain stimulation can help improve voice, swallowing, and coughing for people with Parkinson's disease, so we can find the best ways to support these important functions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10904836 on ClinicalTrials.gov |
What this research studies
This research explores the effects of deep brain stimulation (DBS) on laryngeal functions such as voice, swallowing, and coughing in individuals with Parkinson's disease. By comparing different DBS targets in the brain, the study aims to understand how these interventions can influence essential functions that are often affected by the disease. Patients will be monitored for changes in their ability to speak and swallow, providing valuable insights into the best practices for DBS treatment. The research will involve assessing various stimulation settings and their impact on laryngeal control.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with Parkinson's disease who are considering or have undergone deep brain stimulation surgery.
Not a fit: Patients who do not have Parkinson's disease or those who are not candidates for deep brain stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved DBS techniques that enhance voice and swallowing functions for patients with Parkinson's disease.
How similar studies have performed: While deep brain stimulation has been widely studied for motor symptoms in Parkinson's disease, the specific impact on laryngeal functions is less explored, making this research a novel investigation.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HEGLAND, KAREN W — UNIVERSITY OF FLORIDA
- Study coordinator: HEGLAND, KAREN W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.