Investigating how deep brain stimulation affects ankle muscle control in Parkinson's disease

EFFECTS OF DISEASE AND PALLIDAL DEEP BRAIN STIMULATION ON ANKLE MUSCLE CONTROL IN PARKINSON'S DISEASE

['FUNDING_FELLOWSHIP'] · UNIVERSITY OF MINNESOTA · NIH-10929394

This study is looking at how deep brain stimulation can help people with Parkinson's disease better control their ankle muscles, which may improve their walking and reduce stiffness.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MINNESOTA (nih funded)
Locations1 site (MINNEAPOLIS, UNITED STATES)
Trial IDNIH-10929394 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the effects of deep brain stimulation on ankle muscle control in individuals with Parkinson's disease. It aims to explore the mechanisms behind impaired control of lower limb muscles, particularly the differences in strength between flexor and extensor muscles. By using techniques like transcranial magnetic stimulation, the study will assess how these muscles contribute to gait and rigidity issues in patients. The findings could lead to improved treatment strategies for managing gait deficits in Parkinson's disease.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience gait disturbances and mobility issues.

Not a fit: Patients with Parkinson's disease who do not have significant gait or mobility problems may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better therapeutic approaches for improving mobility and reducing falls in patients with Parkinson's disease.

How similar studies have performed: Previous research has shown that deep brain stimulation can improve certain motor functions in Parkinson's disease, but this specific investigation into ankle muscle control is relatively novel.

Where this research is happening

MINNEAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.