Investigating how daily activity affects Alzheimer's disease
Official title: The role of 24-hour activity in Alzheimer's Disease
Funded at Vanderbilt University Medical Center · NIH-11088911 · Data updated 2026-11-12
This study is looking at how your daily habits, like sleep and exercise, might affect brain health and the risk of developing Alzheimer's and related dementias, and it's for people who want to understand how lifestyle changes could help prevent these conditions before any symptoms show up.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | July 15, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $120,177 |
| NIH project number | 5K01AG083223-03 |
| Project ID | NIH-11088911 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are at risk for Alzheimer's disease or related dementias.
✕Less likely to help
Patients who are already diagnosed with advanced Alzheimer's disease or related dementias may not benefit from this research.
What this research studies
This research explores the relationship between daily activity patterns, including sleep, physical activity, and sedentary behavior, and their impact on Alzheimer's disease and related dementias (ADRD). By using advanced actigraphy to objectively measure these behaviors over time, the study aims to identify how changes in activity may influence cognitive decline and brain health before clinical symptoms appear. Participants will be part of a well-characterized cohort, allowing for a thorough analysis of how lifestyle factors may serve as early prevention strategies against ADRD.
Why it matters
Potential benefit: If successful, this research could lead to new prevention strategies that help delay or reduce the risk of developing Alzheimer's disease.
How similar studies have gone: Previous research has shown promising results in understanding the link between lifestyle factors and cognitive health, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Full, Kelsie Marie — Vanderbilt University Medical Center
- Study coordinator: Full, Kelsie Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.