Investigating how daily activity affects Alzheimer's disease

The role of 24-hour activity in Alzheimer's Disease

NIH-funded research Vanderbilt University Medical Center · NIH-11088911

This study is looking at how your daily habits, like sleep and exercise, might affect brain health and the risk of developing Alzheimer's and related dementias, and it's for people who want to understand how lifestyle changes could help prevent these conditions before any symptoms show up.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-11088911 on NIH RePORTER

What this research studies

This research explores the relationship between daily activity patterns, including sleep, physical activity, and sedentary behavior, and their impact on Alzheimer's disease and related dementias (ADRD). By using advanced actigraphy to objectively measure these behaviors over time, the study aims to identify how changes in activity may influence cognitive decline and brain health before clinical symptoms appear. Participants will be part of a well-characterized cohort, allowing for a thorough analysis of how lifestyle factors may serve as early prevention strategies against ADRD.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are at risk for Alzheimer's disease or related dementias.

Not a fit: Patients who are already diagnosed with advanced Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new prevention strategies that help delay or reduce the risk of developing Alzheimer's disease.

How similar studies have performed: Previous research has shown promising results in understanding the link between lifestyle factors and cognitive health, suggesting that this approach may yield valuable insights.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.