Investigating how daily activities and social factors affect Alzheimer's disease in older adults

Life-space, isolation, and functional exposome study in preclinical Alzheimer's disease and cognitive environments (LIFESPACE)

NIH-funded research Washington University · NIH-11134283

This study is looking at how your daily activities and social connections might affect brain health in older adults with Alzheimer's, using smartwatches and activity trackers to gather helpful information that could lead to earlier detection and better support for those at risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11134283 on NIH RePORTER

What this research studies

This research focuses on understanding the relationship between daily activities, social isolation, and Alzheimer's disease in older adults. By using digital tools like smartwatches and activity trackers, the study aims to collect data on how lifestyle factors influence cognitive health. Researchers will analyze this data to identify patterns that may indicate preclinical Alzheimer's disease and assess how social and environmental factors impact these patterns over time. The goal is to improve early detection and intervention strategies for Alzheimer's disease.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 65 and above, particularly those who may be experiencing early signs of cognitive impairment or social isolation.

Not a fit: Patients who are younger than 65 or those who do not have any cognitive impairment or social isolation issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better early detection methods for Alzheimer's disease and improved strategies to enhance the quality of life for older adults.

How similar studies have performed: Previous research has shown promise in using digital markers to assess cognitive health, indicating that this approach could yield valuable insights.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.