Investigating how cytomegalovirus affects recovery from concussions

The role of cytomegalovirus in the physiological and clinical effects of concussion

NIH-funded research Medical College of Wisconsin · NIH-11012418

This study is looking at how having cytomegalovirus (CMV) might affect how athletes recover from concussions, and it’s for athletes who have had a concussion and want to understand their recovery better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical College of Wisconsin NIH-funded
Lab location1 site (Milwaukee, United States)
Project IDNIH-11012418 on NIH RePORTER

What this research studies

This research explores the impact of cytomegalovirus (CMV) on the recovery process following sport-related concussions (SRC). By analyzing data from a cohort of athletes, the study will assess how CMV serostatus influences physiological and clinical outcomes after a concussion. Participants will undergo MRI scans, clinical assessments, and blood tests at various stages, including pre-injury and post-injury, to identify potential modifiable factors that could personalize treatment and improve recovery. The goal is to enhance understanding of SRC and develop better prognostic models for recovery.

Who could benefit from this research

Good fit: Ideal candidates for this research include athletes who have experienced a sport-related concussion and have undergone relevant assessments.

Not a fit: Patients who have not experienced a concussion or those with pre-existing neurological conditions unrelated to CMV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved recovery strategies for individuals suffering from concussions.

How similar studies have performed: While the role of CMV in other inflammatory diseases has been studied, this specific investigation into its effects on concussion recovery is novel.

Where this research is happening

Milwaukee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.