Investigating how Crohn's disease affects growth differently in boys and girls

Sex Differences in Statural Growth Impairment in Pediatric Crohn's Disease: Part 2

NIH-funded research Children's Research Institute · NIH-11141872

This study is looking at how Crohn's disease affects the growth of children, especially comparing boys and girls, to find out what might be causing any growth issues and how to help kids grow better and stay healthy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionChildren's Research Institute NIH-funded
Lab location1 site (Washington, United States)
Project IDNIH-11141872 on NIH RePORTER

What this research studies

This research focuses on understanding how pediatric Crohn's disease impacts growth in children, particularly examining the differences between boys and girls. It aims to identify the factors that contribute to growth impairment, such as inflammation, genetics, and nutrition. By analyzing data from previous studies, the researchers will explore how inflammation affects hormone levels that regulate growth, with the hypothesis that boys may be more severely impacted. The goal is to improve treatment strategies for children with Crohn's disease to enhance their growth and overall health.

Who could benefit from this research

Good fit: Ideal candidates for this research are children diagnosed with Crohn's disease, particularly those experiencing growth impairment.

Not a fit: Patients without Crohn's disease or those who are not experiencing growth issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better treatment options that promote normal growth in children with Crohn's disease.

How similar studies have performed: Previous studies have shown that understanding sex differences in disease impact can lead to improved treatment strategies, suggesting potential success for this research approach.

Where this research is happening

Washington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.