Investigating how COVID-19 affects the brain
Brain pathophysiology in SARS-CoV-2 disease
This study is looking at how COVID-19 can affect the brain by damaging blood vessels and causing neurological problems, and it's for anyone interested in understanding the potential brain issues linked to the virus and how we might treat them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-11124689 on NIH RePORTER |
What this research studies
This research explores the impact of SARS-CoV-2 on the brain, focusing on how the virus can cause damage to blood vessels and lead to neurological issues. The study examines the role of a specific enzyme, ACE2, which the virus targets, and how its deficiency may contribute to brain dysfunction. By using animal models, researchers will investigate the mechanisms behind these effects and potential treatments that could mitigate the damage caused by the virus. The goal is to better understand the neurological consequences of COVID-19 and identify therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced neurological symptoms following COVID-19 infection.
Not a fit: Patients who have not been infected with SARS-CoV-2 or do not exhibit neurological symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for neurological complications associated with COVID-19.
How similar studies have performed: Other research has shown promising results in understanding the neurological effects of viral infections, suggesting that this approach could yield valuable insights.
Where this research is happening
Washington, United States
- Georgetown University — Washington, United States (Active)
Researchers
- Principal investigator: Sandberg, Kathryn L — Georgetown University
- Study coordinator: Sandberg, Kathryn L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.