Investigating how COVID-19 affects people with sickle cell disease

Epidemiology and Biosocial risk factors for adverse outcomes of COVID-19 in people with sickle cell disease : Analyses of national COVID surveillance registry

['FUNDING_R21'] · UNIVERSITY OF IOWA · NIH-11098655

This study is looking at how COVID-19 affects people with sickle cell disease, especially among African Americans, to better understand the risks and long-term symptoms they might face.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF IOWA (nih funded)
Locations1 site (IOWA CITY, UNITED STATES)
Trial IDNIH-11098655 on ClinicalTrials.gov

What this research studies

This research aims to understand the impact of COVID-19 on individuals with sickle cell disease (SCD), particularly focusing on African Americans who are disproportionately affected. By analyzing data from a national COVID surveillance registry, the study will explore both biological and social risk factors that contribute to severe outcomes in SCD patients. The research will also assess the prevalence of long-COVID symptoms in this population, addressing gaps in previous studies that lacked comprehensive data. Through a data-driven approach, the study seeks to provide a clearer picture of how COVID-19 interacts with SCD and other risk factors.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with sickle cell disease, particularly those who are African American and have experienced COVID-19.

Not a fit: Patients without sickle cell disease or those who have not been affected by COVID-19 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of COVID-19 in patients with sickle cell disease, potentially informing better treatment strategies.

How similar studies have performed: While there have been studies on COVID-19 impacts in various populations, this research specifically targeting sickle cell disease and its unique interactions with COVID-19 is relatively novel.

Where this research is happening

IOWA CITY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: acute phase of SARS-CoV-2 infection, acute SARS-CoV-2 infection, adverse sequelae of coronavirus disease, adverse sequelae of coronavirus disease 2019

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.