Investigating how COVID-19 affects heart artery plaque growth
Mechanistic registry to study whether infection with Corona Virus Disease 2019 (COVID-19) accelerates atherosclerotic plaque progression
This study is looking at whether getting COVID-19 makes heart problems worse for people who already have coronary artery disease, by using special imaging to see how their heart health changes over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10889910 on NIH RePORTER |
What this research studies
This research aims to understand if COVID-19 infection accelerates the progression of atherosclerotic plaque in patients who already have coronary artery disease. By utilizing advanced imaging techniques like coronary computed tomographic angiography (CCTA), the study will measure changes in plaque characteristics and coronary inflammation over time. The research will focus on patients with existing heart conditions to explore the inflammatory responses triggered by COVID-19 and their potential impact on heart health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with pre-existing coronary artery disease who have tested positive for COVID-19.
Not a fit: Patients without coronary artery disease or those who have not been infected with COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of heart disease in patients affected by COVID-19.
How similar studies have performed: Previous research has indicated that viral infections can influence cardiovascular health, suggesting that this approach may yield valuable insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Shaw, Leslee J — Icahn School of Medicine at Mount Sinai
- Study coordinator: Shaw, Leslee J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.