Investigating how COVID-19 affects blood vessels in the brain
Cerebral vascular pathology of COVID-19
['FUNDING_R01'] · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · NIH-10553944
This study is looking at how COVID-19 affects the tiny blood vessels in the brain, which are important for keeping our brains healthy, especially for people dealing with long-term effects of the virus, to help find new ways to treat any related neurological problems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (CORAL GABLES, UNITED STATES) |
| Trial ID | NIH-10553944 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the impact of COVID-19 on the brain's microvessels, which are crucial for maintaining brain health. It aims to explore how the SARS-CoV-2 virus interacts with these blood vessels and contributes to neurological issues, including strokes, particularly in patients experiencing long-term effects of the virus. By examining the inflammatory responses and changes in gene expression related to blood vessel integrity, the study seeks to uncover the mechanisms behind these complications. The findings could provide insights into potential therapeutic targets for patients affected by COVID-19.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have had COVID-19 and are experiencing neurological symptoms or long-COVID effects.
Not a fit: Patients who have not had COVID-19 or do not exhibit any neurological symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for neurological complications associated with COVID-19.
How similar studies have performed: While there is ongoing research into the neurological effects of COVID-19, this specific focus on brain microvessels and their role in stroke development is relatively novel.
Where this research is happening
CORAL GABLES, UNITED STATES
- UNIVERSITY OF MIAMI SCHOOL OF MEDICINE — CORAL GABLES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TOBOREK, MICHAL — UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- Study coordinator: TOBOREK, MICHAL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cerebrovascular Disorders, Brain Vascular Disorders