Investigating how COVID-19 affects Alzheimer's risk in diverse populations
Official title: Biostatistics Core
Funded at University of Texas Hlth Science Center · NIH-10907426 · Data updated 2026-11-12
This study is looking at how COVID-19 and our genes might affect the risk of developing Alzheimer's disease, and it's for people from different backgrounds who have had COVID-19, as we want to learn more about how the virus impacts brain health over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $461,508 |
| NIH project number | 5U19AG076581-02 |
| Project ID | NIH-10907426 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals from diverse ancestral backgrounds, particularly those with a history of COVID-19 infection and concerns about Alzheimer's disease.
✕Less likely to help
Patients who have not been infected with COVID-19 or do not have a family history of Alzheimer's disease may not benefit from this research.
What this research studies
This research focuses on understanding the interactions between SARS-CoV-2 infection and genetic variations that may influence the risk of developing Alzheimer's disease. It involves characterizing individuals from various ancestral backgrounds, including Amerindians and African Americans, to assess the severity of COVID-19, vaccination status, and the impact of different virus variants. Participants will undergo detailed assessments, including cognitive evaluations and neuroimaging, to identify any long-term neurological effects following COVID-19 infection. The study aims to collect and analyze extensive data to enhance our understanding of these interactions over time.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for Alzheimer's disease in populations affected by COVID-19.
How similar studies have gone: Other research has shown promising results in understanding the links between viral infections and neurological conditions, suggesting potential for success in this area.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: Zozus, Meredith Nahm — University of Texas Hlth Science Center
- Study coordinator: Zozus, Meredith Nahm
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.