Investigating how copper affects the spread of triple negative breast cancer
Copper-mediated metabolic reprogramming and ECM alterations in TNBC metastasis
This study is looking at how copper affects the growth and spread of triple negative breast cancer, with the goal of finding new ways to help patients by potentially slowing down the cancer's progression.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11079650 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of copper in the spread of triple negative breast cancer (TNBC), a type of cancer known for its aggressive nature and poor response to treatment. The study aims to explore how copper influences cancer cell metabolism and the environment that supports tumor growth and spread. By examining the effects of copper depletion on cancer cells and their surrounding tissue, researchers hope to identify new therapeutic strategies that could prevent or reduce metastasis in TNBC patients. The approach includes both laboratory studies using animal models and analysis of human tissue samples.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with triple negative breast cancer who are experiencing or at high risk for metastatic disease.
Not a fit: Patients with non-triple negative breast cancer or those who are not currently experiencing metastatic disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that specifically target the metastatic processes in TNBC, potentially improving patient outcomes.
How similar studies have performed: Previous research has shown promise in targeting metal metabolism in cancer therapy, suggesting that this approach could be a viable strategy for treating TNBC.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Mittal, Vivek — Weill Medical Coll of Cornell Univ
- Study coordinator: Mittal, Vivek
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.