Investigating how complex genetic mutations contribute to evolution and disease.

New Genes and Adaptation

NIH-funded research University of North Carolina Charlotte · NIH-10797414

This study is looking at how certain gene changes in fruit flies can help them adapt to their environments, and it hopes to find out if similar changes in humans could affect health and diseases.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of North Carolina Charlotte NIH-funded
Lab location1 site (Charlotte, United States)
Project IDNIH-10797414 on NIH RePORTER

What this research studies

This research focuses on understanding complex mutations in genes that can lead to the formation of new genes and changes in gene expression, which are important for evolutionary adaptation. Using fruit flies as a model, the study aims to identify these mutations and their effects on local adaptation in changing environments. The findings will also be translated to human health, exploring how similar mutations may impact diseases in humans. By examining these genetic changes, the research seeks to uncover broader patterns that could apply across different species.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with genetic conditions or diseases that may be influenced by complex mutations.

Not a fit: Patients with conditions unrelated to genetic mutations or those not affected by complex genetic changes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of genetic factors in diseases and lead to new approaches for treatment and prevention.

How similar studies have performed: Other research has shown success in understanding genetic mutations and their role in evolution, but this specific approach is relatively novel.

Where this research is happening

Charlotte, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancerDiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.