Investigating how cognitive behavioral therapy can improve sleep and cognitive function in older adults with insomnia to prevent Alzheimer's disease.
Primary Prevention of Alzheimer's disease: Examining the effects of cognitive behavioral therapy on cognitive function and amyloid-beta in older adults with symptoms of insomnia
This study is looking at how a special therapy for sleep problems can help older adults think better and possibly slow down memory loss related to Alzheimer's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Medical Center NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project ID | NIH-10689865 on NIH RePORTER |
What this research studies
This research focuses on the impact of cognitive behavioral therapy for insomnia (CBT-I) on cognitive function in older adults experiencing sleep disturbances. It aims to determine whether improving sleep quality through CBT-I can slow cognitive decline and potentially delay the onset of Alzheimer's disease. The study will involve older adults with insomnia, assessing changes in their cognitive abilities and amyloid-beta levels over time. By targeting sleep issues, this research seeks to explore a novel approach to Alzheimer's disease prevention.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who experience symptoms of insomnia and are at risk for cognitive decline.
Not a fit: Patients who do not have insomnia or significant cognitive concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new method for preventing Alzheimer's disease by improving sleep quality in older adults.
How similar studies have performed: While lifestyle interventions for Alzheimer's prevention have been explored, the specific use of CBT-I for this purpose is a novel approach that has not been extensively tested.
Where this research is happening
Kansas City, United States
- University of Kansas Medical Center — Kansas City, United States (Active)
Researchers
- Principal investigator: Siengsukon, Catherine F — University of Kansas Medical Center
- Study coordinator: Siengsukon, Catherine F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.