Investigating how cocoa supplementation affects aging and inflammation

Effect of randomized cocoa supplementation on inflammaging and epigenetic aging

NIH-funded research Augusta University · NIH-10843061

This study is looking at whether taking a cocoa supplement can help older adults feel younger and reduce inflammation, with the hope of slowing down aging and lowering the risk of diseases like heart problems and cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAugusta University NIH-funded
Lab location1 site (Augusta, United States)
Project IDNIH-10843061 on NIH RePORTER

What this research studies

This research explores the effects of cocoa supplementation on aging and inflammation in older adults. It involves a large-scale randomized controlled trial where participants will receive either a cocoa extract supplement or a placebo to assess its impact on epigenetic aging and inflammatory markers. The study aims to determine if cocoa can help slow down the aging process and reduce the risk of age-related diseases. Participants will be monitored for health outcomes related to cardiovascular disease and cancer.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 65 and older who are interested in improving their health and potentially reducing their risk of age-related diseases.

Not a fit: Patients under the age of 65 or those with specific contraindications to cocoa consumption may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide insights into dietary interventions that promote healthier aging and reduce inflammation-related health risks.

How similar studies have performed: Previous research has shown promising results regarding the health benefits of cocoa, but this specific approach focusing on epigenetic aging is relatively novel.

Where this research is happening

Augusta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.