Investigating how chronic stress affects aging and diseases in women
MAE-WEST SCORE Project 3 Animal
This study is looking at how long-term stress affects aging and health in women, especially in relation to diseases like Alzheimer's, to find ways to help reduce these health issues as women get older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10903843 on NIH RePORTER |
What this research studies
This research focuses on understanding how chronic stressors contribute to aging and the development of diseases, particularly in women. It examines the differences in biological aging between sexes and how these differences may lead to conditions like Alzheimer's disease and related dementias. The study aims to identify the mechanisms behind these disparities, particularly looking at inflammatory mediators that may influence multi-organ dysfunction. By exploring these factors, the research seeks to uncover potential interventions to reduce the burden of age-related diseases in women.
Who could benefit from this research
Good fit: Ideal candidates for this research are women over the age of 21 who are at risk for Alzheimer's disease or related dementias.
Not a fit: Patients who are male or under the age of 21 may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that reduce the risk of Alzheimer's disease and related dementias in women.
How similar studies have performed: Previous research has shown success in understanding sex differences in aging and disease, but this specific approach is novel in its focus on inflammatory mediators.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Shyy, John Yj — Cedars-Sinai Medical Center
- Study coordinator: Shyy, John Yj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.