Investigating how chronic stress affects aging and diseases in women
MAE-WEST SCORE Project 1 Population
This study is looking at how long-term stress affects aging and health, especially in women, to understand why they might be more likely to develop conditions like Alzheimer's disease, and it hopes to find ways to help reduce these health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10903839 on NIH RePORTER |
What this research studies
This research focuses on understanding how chronic stressors contribute to aging and the development of diseases, particularly in women. It examines the differences in biological aging between sexes and how these differences may lead to a higher prevalence of conditions like Alzheimer's disease and related dementias in women. The study aims to identify the mechanisms behind these disparities, particularly looking at inflammatory mediators that may influence multi-organ dysfunction. By exploring these factors, the research seeks to uncover potential interventions to reduce the burden of age-related diseases in women.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing age-related cognitive decline or those at risk for Alzheimer's disease and related dementias.
Not a fit: Patients who are not women or those who do not have concerns related to aging or Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that reduce the risk of Alzheimer's disease and related dementias in women.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in aging and related diseases, indicating that this approach has potential for success.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Cheng, Susan — Cedars-Sinai Medical Center
- Study coordinator: Cheng, Susan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.