Investigating how chronic pain affects heart and muscle function
Official title: Cardiovascular and neuromuscular issues in chronic pain
Funded at University of Utah · NIH-11064007 · Data updated 2026-11-12
This study is looking at how living with chronic pain affects your heart health and muscle strength, especially when you exercise, and it will compare people with chronic pain to those who are healthy to see how pain changes things like heart rate and blood pressure, while also testing new ways to help manage pain better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $762,557 |
| NIH project number | 5R01HL170007-02 |
| Project ID | NIH-11064007 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic pain, particularly those experiencing pain in the lower limbs.
✕Less likely to help
Patients without chronic pain or those with acute pain conditions may not benefit from this research.
What this research studies
This research aims to understand the effects of chronic pain on cardiovascular health and muscle function. It will explore how chronic pain influences the body's response to exercise and the mechanisms behind these changes. By comparing patients with chronic pain to healthy individuals, the study will assess how pain impacts heart rate, blood pressure, and overall physical performance. Innovative pain management strategies will also be evaluated to improve circulatory control in these patients.
Why it matters
Potential benefit: If successful, this research could lead to better pain management strategies that improve cardiovascular health and physical function for patients with chronic pain.
How similar studies have gone: Previous research has indicated that understanding the relationship between chronic pain and cardiovascular function can lead to significant advancements in treatment approaches.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Amann, Markus — University of Utah
- Study coordinator: Amann, Markus
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.