Investigating how chronic low oxygen levels affect depression risk in older women.
Sex-based study of chronic hypoxia-related vulnerability to depression: age effects
['FUNDING_R21'] · UNIVERSITY OF UTAH · NIH-11187100
This study is looking at how low oxygen levels might affect the risk of depression in older women, especially those over 65, to find new ways to help improve their mental health.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-11187100 on ClinicalTrials.gov |
What this research studies
This research explores the relationship between chronic low oxygen levels and the risk of major depressive disorder (MDD) in older adults, particularly focusing on women over 65. It utilizes a novel animal model to simulate conditions of chronic hypoxia, which occurs at high altitudes, to observe its effects on mental health. The study aims to understand how biological factors, such as inflammation and cognitive decline, interact with environmental conditions to influence depression risk. By examining these interactions, the research seeks to identify potential new treatment strategies for those affected by depression in later life.
Who could benefit from this research
Good fit: Ideal candidates for this research are women aged 65 and older who are experiencing symptoms of depression or are at risk for developing major depressive disorder.
Not a fit: Patients under the age of 65 or those who do not have a history of depression may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for older women suffering from depression, particularly those living in high-altitude areas.
How similar studies have performed: Previous research has indicated that environmental factors like altitude can significantly impact mental health, suggesting that this approach may yield valuable insights.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KANEKAR, SHAMI — UNIVERSITY OF UTAH
- Study coordinator: KANEKAR, SHAMI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.