Investigating how chemical mixtures affect bone health in adolescents

Endocrine disrupting chemical mixtures and bone health in adolescence

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10918262

This study is looking at how certain chemicals that can disrupt hormones might affect bone health in teenagers, so if you’re part of a previous study and are around 17 years old, we’d love to see how these chemicals may have impacted your bones.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10918262 on NIH RePORTER

What this research studies

This research focuses on understanding the impact of endocrine disrupting chemicals (EDCs) on bone health during adolescence, a critical period for bone development. The study will follow participants from a previous birth cohort study, assessing their exposure to various EDCs and measuring their bone mineral density and strength at around 17 years of age. By analyzing the relationship between these chemical exposures and bone health, the research aims to identify potential risks and inform future health guidelines. Participants will undergo biomarker testing to evaluate their exposure levels and bone health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 17 years who have been part of the Health Outcomes and Measures of the Environment (HOME) Study cohort.

Not a fit: Patients who are not part of the HOME Study cohort or those outside the age range of 12 to 20 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for bone health issues in adolescents, potentially reducing the risk of osteoporosis later in life.

How similar studies have performed: Previous studies have shown associations between EDC exposure and bone health, but this research aims to provide more comprehensive insights into the effects during adolescence, making it a novel approach.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.