Investigating how changes in timing affect brain development.
Long-term neural consequences of altered critical period timing.
['FUNDING_FELLOWSHIP'] · WASHINGTON UNIVERSITY · NIH-11072530
This study is looking at how different stages of brain development affect how brain cells connect and work together, especially focusing on a type of support cell called astrocytes, to help us understand how these changes might influence behavior and brain function.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11072530 on ClinicalTrials.gov |
What this research studies
This research explores how the timing of critical periods in brain development influences the formation and function of neural circuits. By studying animal models, particularly focusing on astrocytes and their role in signaling, the research aims to understand how these signals affect the wiring of neural circuits during crucial developmental windows. The methodology includes genetic screening and manipulation of astrocyte signaling to observe changes in critical period dynamics and their impact on behavior and neural function.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with autism spectrum disorder or related developmental conditions.
Not a fit: Patients with fully developed neural circuits and no history of developmental disorders may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the timing of brain development, potentially informing interventions for conditions like autism spectrum disorder.
How similar studies have performed: Previous research has shown promising results in understanding critical periods and their regulation, indicating that this approach has potential for significant findings.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: POSTOLACHE, MAGGIE — WASHINGTON UNIVERSITY
- Study coordinator: POSTOLACHE, MAGGIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.