Investigating how changes in blood pressure may contribute to dementia.
Epidemiologic, imaging and pathological studies of the role of blood pressure variability in dementia etiology
This study is looking at how changes in blood pressure might affect the risk of developing Alzheimer's and other types of dementia, and it’s for people who want to help us understand this connection better by sharing their health information.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard School of Public Health NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11075259 on NIH RePORTER |
What this research studies
This research explores the connection between blood pressure variability and the development of Alzheimer's disease and related dementias. By analyzing data from multiple cohort studies in the US and Europe, the project aims to quantify how fluctuations in blood pressure over time may influence dementia risk. The study will also investigate the biological mechanisms that link blood pressure changes to dementia, potentially leading to new prevention strategies. Patients may be involved in providing data or participating in assessments related to their blood pressure and cognitive health.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults who have experienced fluctuations in blood pressure and are at risk for Alzheimer's disease or related dementias.
Not a fit: Patients with stable blood pressure and no risk factors for dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing Alzheimer's disease and related dementias by managing blood pressure variability.
How similar studies have performed: Previous research has indicated a potential link between blood pressure variability and cardiovascular health, but this specific approach to Alzheimer's disease is relatively novel.
Where this research is happening
Boston, United States
- Harvard School of Public Health — Boston, United States (Active)
Researchers
- Principal investigator: Ma, Yuan — Harvard School of Public Health
- Study coordinator: Ma, Yuan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.