Investigating how certain proteins help archaea produce and consume methane
Developing Methanosarcina spp. as a model system to study cytochromes c and their role in archaeal methane metabolism
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF CALIFORNIA BERKELEY · NIH-10929298
This study is looking at tiny microorganisms that help break down methane, a gas that affects our climate, to learn how they work and grow, which could help us understand more about methane's impact on the environment.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA BERKELEY (nih funded) |
| Locations | 1 site (BERKELEY, UNITED STATES) |
| Trial ID | NIH-10929298 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of cytochromes c in methane-metabolizing archaea, which are microorganisms that play a significant role in the global methane cycle and climate change. The project aims to develop a genetically tractable model system using Methanosarcina acetivorans to explore the molecular mechanisms behind methane metabolism. By utilizing advanced genetic and biochemical techniques, the research seeks to characterize how these proteins function and their importance in energy conservation and growth in these archaea. This could provide insights into the broader implications of methane production and consumption in the environment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in environmental health and the impacts of methane on climate change.
Not a fit: Patients with conditions unrelated to methane metabolism or environmental health may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of methane emissions, potentially aiding in climate change mitigation efforts.
How similar studies have performed: While the specific approach of using Methanosarcina acetivorans is novel, similar research has shown promise in understanding microbial roles in methane metabolism.
Where this research is happening
BERKELEY, UNITED STATES
- UNIVERSITY OF CALIFORNIA BERKELEY — BERKELEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GUPTA, DINESH — UNIVERSITY OF CALIFORNIA BERKELEY
- Study coordinator: GUPTA, DINESH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.