Investigating how certain proteins affect heart disease in people with type 1 diabetes
Substance P Metabolites and Receptors in the Pathogenesis of Cardiac Disease in Type 1 Diabetes
This study is looking at how a protein called substance P might help protect the hearts of people with type 1 diabetes, and it hopes to find new ways to prevent or improve heart problems related to the condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | West Virginia University NIH-funded |
| Lab location | 1 site (Morgantown, United States) |
| Project ID | NIH-11074273 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of substance P and its metabolites in the development of heart disease among individuals with type 1 diabetes. The study uses animal models to explore how these proteins can protect against heart damage and improve heart function. By identifying new treatment approaches that target specific receptors involved in cardiac health, the research aims to find ways to prevent or reverse heart complications associated with diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 1 diabetes who are at risk for cardiovascular complications.
Not a fit: Patients without type 1 diabetes or those who do not have cardiovascular issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that prevent heart disease in patients with type 1 diabetes.
How similar studies have performed: Previous research has shown promising results in using similar approaches to protect heart health in diabetes, indicating potential for success in this study.
Where this research is happening
Morgantown, United States
- West Virginia University — Morgantown, United States (Active)
Researchers
- Principal investigator: Levick, Scott P — West Virginia University
- Study coordinator: Levick, Scott P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.