Investigating how certain molecules affect the risk of pulmonary arterial hypertension
Eicosanoid Pathways Underlying Disease Risk in Pulmonary Arterial Hypertension
['FUNDING_CAREER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11001975
This study is looking at how changes in metabolism and certain markers in the body affect pulmonary arterial hypertension (PAH), with the goal of finding better ways to treat this serious condition and help patients feel better.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11001975 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of metabolic changes and specific molecular markers in the progression of pulmonary arterial hypertension (PAH). The approach involves both human studies and experimental models to identify potential biomarkers that could lead to better treatment options. The research aims to enhance the knowledge of how endothelial dysfunction contributes to PAH, which is a serious condition that can lead to heart failure if not managed properly. By developing sensitive methods to detect these biomarkers, the research seeks to improve patient outcomes through more personalized treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pulmonary arterial hypertension or those at risk for developing this condition.
Not a fit: Patients with other forms of pulmonary hypertension unrelated to the mechanisms being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for patients with pulmonary arterial hypertension.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for other cardiovascular diseases, suggesting that this approach could yield valuable insights for pulmonary arterial hypertension as well.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALOTAIBI, MONA A — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: ALOTAIBI, MONA A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.