Investigating how certain lipid transport proteins work in bacteria and eukaryotes
Structure and function of the LetA lipid transport family across bacteria and eukaryotes
['FUNDING_CAREER'] · JOHNS HOPKINS UNIVERSITY · NIH-11033544
This study is all about understanding how certain proteins help move fats in and out of cells, which could lead to new ways to treat infections, and it's being led by Dr. Cristina Santarossa, who is also working to encourage more diversity in science.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11033544 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the structure and function of the LetA lipid transport family, which plays a crucial role in the movement of lipids across cell membranes in both bacteria and eukaryotic cells. The principal investigator, Dr. Cristina Santarossa, aims to master lipidomics, a technique that analyzes lipid molecules, to explore how these proteins function. The project includes training in microbiology and outreach activities to promote diversity in the biomedical sciences, ultimately preparing Dr. Santarossa for an independent academic career. Patients may benefit indirectly from this research as it could lead to new insights into bacterial behavior and potential treatments for infections.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with bacterial infections or those interested in advancements in microbiology.
Not a fit: Patients with non-bacterial infections or conditions unrelated to lipid transport mechanisms may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating bacterial infections by targeting lipid transport mechanisms.
How similar studies have performed: Other research has shown success in understanding lipid transport mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SANTAROSSA, CRISTINA — JOHNS HOPKINS UNIVERSITY
- Study coordinator: SANTAROSSA, CRISTINA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.