Investigating how certain immune cells contribute to cell death in retinal detachment.
Defining the Role of Retinal Microglia and Infiltrating Monocytes on Photoreceptor Cell Death in Retinal Detachment
['FUNDING_CAREER'] · UNIVERSITY OF ILLINOIS AT CHICAGO · NIH-11128671
This study is looking at how certain immune cells affect the death of light-sensitive cells in the eye when the retina gets detached, with the hope that what we learn can help create better treatments for people dealing with this condition.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT CHICAGO (nih funded) |
| Locations | 1 site (Chicago, UNITED STATES) |
| Trial ID | NIH-11128671 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of specific immune cells, known as mononuclear phagocytes, in the process of photoreceptor cell death that occurs during retinal detachment. The project aims to enhance the skills of the principal investigator while employing advanced laboratory techniques to explore this critical area of ophthalmology. By collaborating with a multidisciplinary mentoring team, the research seeks to uncover mechanisms that could lead to improved treatments for retinal detachment. Patients may benefit from insights gained through this research that could inform future therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are adults who are at risk of or have experienced retinal detachment.
Not a fit: Patients with retinal detachment who are under 21 years old or have other unrelated ocular conditions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that protect photoreceptor cells and preserve vision in patients experiencing retinal detachment.
How similar studies have performed: Previous research has shown promise in understanding the role of immune cells in retinal diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Chicago, UNITED STATES
- UNIVERSITY OF ILLINOIS AT CHICAGO — Chicago, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAIDANA, DANIEL ENRIQUE — UNIVERSITY OF ILLINOIS AT CHICAGO
- Study coordinator: MAIDANA, DANIEL ENRIQUE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.