Investigating how certain hormones affect social connections and stress responses
Kappa opioid and oxytocin interactions in social buffering and separation
This study is looking at how social connections affect health by exploring the roles of certain hormones in titi monkeys, which are known for their close friendships, to help us understand how these hormones influence our relationships and well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11019849 on NIH RePORTER |
What this research studies
This research explores the biological mechanisms behind social connections and their impact on health, particularly focusing on the interactions between the kappa opioid system and oxytocin. By studying titi monkeys, which are known for their strong social bonds, the researchers aim to understand how these hormones influence both the positive and negative effects of social relationships. The study will involve observing the monkeys' behaviors and physiological responses to social stress and separation, providing insights that could be difficult to obtain in human studies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing acute stress or those interested in the biological underpinnings of social relationships.
Not a fit: Patients who are not experiencing acute stress or do not have an interest in the biological aspects of social connections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing social support systems and improving mental health outcomes.
How similar studies have performed: While the specific interactions of the kappa opioid system and oxytocin in social contexts are less studied, related research has shown promising results in understanding social behaviors and stress responses in animal models.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Bales, Karen L. — University of California at Davis
- Study coordinator: Bales, Karen L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.